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However no reviews was focused on all the glutamate heterore
2021-10-20

However, no reviews was focused on all the glutamate heteroreceptor complexes and how to understand why some were formed and not others in the glutamate synapses and their extrasynaptic regions. These receptor complexes are present on the glutamate nerve terminals and the dendritic spines on which t
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br Experimental section br Acknowledgments MIN cells were ki
2021-10-19

Experimental section Acknowledgments MIN6 848 receptor were kindly provided by Dr. Junichi Miyazaki, Osaka University. This research was supported in part by the Ministry of Education, Culture, Sports, Science and Technology of Japan (JP16H05099 and JP18H04609 to K.H., and JP16H06574 to T.U.)
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br Materials and methods Manganese chloride MnCl H O glutama
2021-10-19

Materials and methods Manganese chloride (MnCl2·4H2O), glutamate, glutamine, Lucifer Yellow, polyclonal anti-GFAP and MTT assay kits were purchased from Sigma Chemical Co. (St. Louis, MO). Dulbecco's Modified Eagle's Medium-F12 (DMEM-F12) with Earle's salts, foetal bovine serum, penicillin, and s
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Bile acids BAs are detergent like amphipathic
2021-10-19

Bile acids (BAs) are detergent-like amphipathic molecules synthesized from cholesterol in the liver, stored in the gallbladder, and released into the intestine after food intake in order to facilitate the agomelatine of dietary lipids and liposoluble vitamins. BAs travel along the intestine and onc
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br Methods br Results We have previously
2021-10-19

Methods Results We have previously used ß-hex assays in HeLa Fluoxymesterone to study the role of lysosomal exocytosis on transition metal clearance and the effects of transition metals on lysosomal exocytosis [26], [29], [40]. ß-hex is a lysosomal enzyme, the delivery of which to the extracel
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br Introduction The coronary vasculature is required
2021-10-19

Introduction The coronary vasculature is required for supplying oxygenated blood to the cardiac muscle. Proper coronary blood circulation is essential for embryonic and adult cardiac tissue homeostasis. Defects associated with the coronary function leads to myocardial ischemia, infarction, and he
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Ultimately the change of maturation ratio
2021-10-19

Ultimately, the change of maturation ratio of the Leydig cell caused reducing of INSL3 expression undoubtedly. INSL3 (insulin-like 3) is a hormone produced mainly in gonadal tissues. It was discovered to participate in development of urogenital tract. The mutations of this gene is one cause of crypt
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Lieber have discussed alcohol outside the context of
2021-10-19

Lieber (2000), have discussed alcohol outside the context of hepatitis C infection exerts specific pathologic effects on the liver. Liver biopsies in patients with hepatitis C who drink alcohol are generally consistent with hepatitis C alone, with portal-based pathology, rather than alcoholic injury
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Various inhibitors have been developed to target molecules p
2021-10-19

Various inhibitors have been developed to target molecules present in these pathways. They include both man-made monoclonal cdc42 pathway as well as small molecule membrane permeable inhibitors that often target kinases or phosphatases [5], [338], [348], [364]. In summary, these pathways are frequen
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Acknowledgments This research was supported by the Korea
2021-10-19

Acknowledgments This research was supported by the Korea Research Institute of Chemical Technology (KRICT) funded by the Ministry of Science, ICT & Future Planning (KK1703-G00, KK1707-C05, SI1707-02, KK-1607-C09, and SKO1707C05) and a grant of the Korea Health Technology R&D Project through the Kor
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hmg-coa reductase The effects of opioids such as morphine ar
2021-10-19

The effects of opioids such as morphine are mediated through the opioid receptors. Opioid receptors are widely expressed both peripherally and in the CNS (Chen et al., 1993, Evans et al., 1992). The opioid agonist morphine has been shown to amplify the effect of the tubular cell-gp120 interaction on
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br The presence of an active glyoxalase
2021-10-19

The presence of an active glyoxalase pathway in an apicomplexan parasite was first reported in Plasmodium falciparum-infected erythrocytes (Vander Jagt et al., 1990). Some years later, glyoxalase I and both glyoxalase II enzymes were characterized in this parasite (Akoachere et al., 2005, Iozef et
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Moreover we revealed that alanine and taurine a
2021-10-19

Moreover, we revealed that β-alanine and taurine, a structural analog of β-alanine, have different receptor affinity in the SG neurons of the spinal dorsal horn. Additionally, previous studies indicate that taurine regulates nociceptive information at the spinal cord level, and we have previously de
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Interestingly mGlu and mGlu receptors differ
2021-10-19

Interestingly, mGlu2 and mGlu3 receptors differ notably by their cellular distribution. Whereas mGlu2 receptors are mostly neuronal, mGlu3 receptors are expressed both in glia and in neurons. In neurons, mGlu3 receptors are present at the post-synapse and in presynaptic elements (Tamaru et al., 2001
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br Acknowledgements This work is supported by the Cognitive
2021-10-19

Acknowledgements This work is supported by the Cognitive Sciences and Technologies Council of Iran (CSTC, Grant No. 95P31), the Iran National Science Foundation (INSF) and the Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran. The authors wish to thank Dr. Ayat Kaeidi for his
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