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We report here the case
2022-10-13
We report here the case of a patient with probable genetic prion disease with a Creutzfeldt-Jakob disease-like phenotype associated with a rare PRNP E196K mutation who initially exhibited atypical clinical manifestations principally characterized by behavioral abnormalities. Case report An 80-ye
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Overall we found maternal antibiotics to be associated
2022-10-13
Overall, we found maternal URB597 to be associated with improved outcomes. In these multiple logistic regression models, high postnatal empiric infant antibiotic exposure was not significantly associated with risk for NEC or LOS. However, consistent with previous studies,5, 6 receipt of high empir
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br Acknowledgments This work was supported
2022-10-13
Acknowledgments This work was supported by grants from the “Agence Nationale de la Recherche” ANR-09-CESA-006 program, the Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail (Anses, Project n° 2012-2-077) and the Interdisciplinary Program “Longévité et Viei
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cid calculator br Introduction Alzheimer s disease AD is a n
2022-10-13
Introduction Alzheimer's disease (AD) is a neurodegenerative disorder and the leading cause of dementia. It is characterized by progressive and irreversible damage to different cid calculator areas, resulting in cognitive impairment and behavioral changes (O'Neill, 2013, De Strooper and Karran,
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Tephrosia purpurea Linn pers Fabaceae a widely growing
2022-10-13
Tephrosia purpurea (Linn.) pers, (Fabaceae), a widely growing herbaceous perennial is reported to exhibit significant anti-hyperglycemic activity in animal models [7], [8], [9] as well as able to delay the development of diabetic complications [10], [11]. Recently, we have reported T. purpurea for i
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br Mechanisms of specific immunotherapy Several mechanisms
2022-10-13
Mechanisms of specific immunotherapy Several mechanisms may be involved in specific immunotherapy of EAMG by active immunization with the therapeutic vaccine in IFA. During the therapy, the therapeutic benefits result from diversion of autoantibody specificities away from pathogenic extracellular
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br Materials and methods br Results To
2022-10-12
Materials and methods Results To examine the time and organ specific effect of normal photoperiod and dark environment on the Sennoside D of different SlHXKs and on the enzyme activities, these parameters were determined in different leaf positions of tomato plants. Under control conditions, t
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Studies conducted in our laboratory thus far have shown that
2022-10-12
Studies conducted in our laboratory, thus far, have shown that HKDC1 is broadly expressed [28]. Using the first developed HKDC1 mouse model, we found that complete loss of HKDC1 function is embryonic lethal, similar to other HKs [29,30]. Further studies using HKDC1 heterozygous knockout mice showed
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Human immunodeficiency virus type HIV is responsible for the
2022-10-12
Human immunodeficiency virus type 1 (HIV-1) is responsible for the ornidazole pandemic; notification is compulsory in Brazilian blood banks since 1988. From 1980 to 2016, the Brazilian MH reported 882,810 HIV/AIDS cases, with 52.3% in the southeast region. HIV/HCV co-infection has been associated
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br Materials and methods br Results br Discussion Early stud
2022-10-12
Materials and methods Results Discussion Early studies in the mid 1980s tentatively identified cCMP in tissues using fast atom bombardment MS [3], [4], but specificity and sensitivity of the method are insufficient for unequivocal identification as compared to modern MS analytical methods.
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br S NO signalling during the plant immune response Redox
2022-10-12
(S)NO signalling during the plant immune response Redox signalling molecules must exhibit specificity for their target substrate. Moreover, a given redox-based modification must be reversible to ensure transient signalling. Oxidative cysteine (Cys) modifications are integral to a variety of redox
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IL had marked effects on the
2022-10-12
IL-33 had marked effects on the inflammatory response in human adipocytes beyond GPR84, with a substantial stimulation of the expression of a selected group of cytokine and chemokine genes. Expression of IL1B, a co-member of the IL-1 superfamily, was strongly up-regulated by IL-33, as was IL6 and CX
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br Glycoprotein Production br Strategies to Obtain Glycoprot
2022-10-12
Glycoprotein Production Strategies to Obtain Glycoprotein Compositional Homogeneity Glycoproteins are modified by glycosyltransferases and glycosylhydrolases in the ER and Golgi; however, the degree of remodeling for each glycan on each protein is not explicitly defined by a template (Moremen
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EAAT glutamate uptake is driven by the co transport
2022-10-12
EAAT glutamate uptake is driven by the co-transport of three sodium ions and one proton, as well as the counter-transport of one potassium ion (Fig. 1B). This complex stoichiometry frees up enough energy to permit Glutathione (GSH/GSSG/Total) Fluorometric Assay Kit of glutamate into the cell agains
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br Results br Discussion Arc p forms a
2022-10-12
Results Discussion Arc1p forms a ternary complex with ScMetRS and ScGluRS and acts as a tIF in trans of both synthetases to improve their catalytic efficiencies.20., 24. The human homolog of Arc1p, the p43 protein, is associated within a multi-enzyme complex containing nine aminoacyl-tRNA synt
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