• calcium channel blockers Thompson transformations parametric

  2018-11-12

  

  Thompson transformations (parametric “warping” based on quadratic functions, Wilkinson, 2005, pp. 223–224) as illustrated in Figure 3 allow positive and negative transformations based on parameters P1–P10. Of these, the presented generative system uses the six parameters P1, P2, P3, P6, P7 and P8. P

• The rise of the balance between

  2018-11-12

  

  The rise of the balance between rationality and creativity as the central concept in the design process that characterizes design education is an important development of rationalism as the ordering paradigm. Brown and Yates (2001) recognized that two main concepts remain central to architectural de

• ketotifen fumarate To validate the system we conducted anoth

  2018-11-12

  

  To validate the system, we conducted another round of studies with the design practitioners. We invited one of the three practitioners who participated in the previous interviews and asked this practitioner to complete an interior design using our system. The other two practitioners were provided wi

• Introduction Primary thyroid lymphoma is rare accounting

  2018-11-12

  

  Introduction Primary thyroid lymphoma is rare, accounting for Methods Results Ten patients with primary thyroid lymphoma were identified. Of these, eight had DLBCL, and two had MALT lymphoma. Patient demographics, pathological diagnoses, and disease stages are listed in Table 1. In total, six

• nuclear receptors Introduction Primary thyroid lymphoma is r

  2018-11-12

  

  Introduction Primary thyroid lymphoma is rare, accounting for Methods Results Ten patients with primary thyroid lymphoma were identified. Of these, eight had DLBCL, and two had MALT lymphoma. Patient demographics, pathological diagnoses, and disease stages are listed in Table 1. In total, six

• It has been shown that in several cancers

  2018-11-12

  

  It has been shown that, in several cancers, only a minority of the cancer pyruvate dehydrogenase kinase are able to initiate the formation of new tumors. These cancer-initiation cells are called CSCs, and in several studies the CD44 adhesion molecule has been demonstrated to be expressed specificall

• glycine transporter Obesity in general is a predisposing

  2018-11-12

  

  Obesity in general is a predisposing factor of OA. There is a strong association between overweight and hip and knee OA. However, the association between overweight and ankle OA remains unclear. In Frey and Zamora\'s study regarding overweight and ankle OA, a total of 887 women and 535 men were incl

• According to the mechanism injuries

  2018-11-12

  

  According to the mechanism, injuries were divided into three subgroups: motorcycle accident, car accident, and others (including assaults, sports-related injuries, and industrial accidents). The severity of head injury on admission was assessed using the GCS, and injuries were classified as severe (

• Based on the approach outlined above we

  2018-11-12

  

  Based on the approach outlined above, we determined that almost all foods include macronutrients, vitamins, phytochemicals, and even toxins that affect immunomodulation, activation or suppression of signal transduction, and metabolic regulation. Moreover, different experiments performed with the sam

• Owing to their extremely complex anatomical

  2018-11-12

  

  Owing to their extremely complex anatomical structures in mammals and humans, identification of stem cell niches has proven to be difficult (Li and Xie, 2005). Consequently, in vivo studies to elucidate signals that regulate stem cell activity suffered from this circumstance. Medical application of

• rgd peptide Regarding JNK phosphorylation levels were either

  2018-11-12

  

  Regarding JNK, phosphorylation levels were either moderately (for JNK 1) or significantly increased (for JNK 2/3) at 5μM SB203580 compared to DMSO controls; these effects were further pronounced at 30μM (Figs. 5 A–B, schema in Figs. 6 C–D). This suggests a concentration-dependent activation of JNK b

• br Materials and methods br Results

  2018-11-12

  

  Materials and methods Results and discussion In order to evaluate the staining properties of CDy1 in a format compatible with high-throughput screening, we transduced MEFs with different combinations of Oct4, Sox2, Klf-4 and c-Myc and seeded them in 96 or 384-well plates using a 4:1 (transduce

• br Experimental Procedures Drosophila stocks are described i

  2018-11-12

  

  Experimental Procedures Drosophila stocks are described in the Supplemental Experimental Procedures. Introduction Primitive hematopoietic progenitors arise from the yolk sac in mammals and generate red blood orexin (RBCs), thereby providing oxygen to the rapidly developing embryos (Orkin and

• To the best of our knowledge only

  2018-11-12

  

  To the best of our knowledge, only three metabolites, L-threonine, butyrate, and vitamin C, have been identified so far that act as epigenetic modulators of ESC self-renewal and/or somatic cell reprogramming (Mali et al., 2010; Shyh-Chang et al., 2013; Wang et al., 2009). Interestingly, L-threonine,

• br Experimental Procedures br Author Contributions br Acknow

  2018-11-12

  

  Experimental Procedures Author Contributions Acknowledgments Introduction The cornea is a multilayered, transparent, and avascular structure forming the anterior part of the eye. Its outermost layer, the corneal epithelium, is exposed to the external environment and thereby needs to be r

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